Projects and Experiences

2025 – 2026
Comprehensive Review on Vagus Nerve Stimulation (VNS)
First-authored a landmark systematic review on Vagus Nerve Stimulation, synthesizing extensive clinical and preclinical evidence to create the field's most comprehensive analysis and establish an evidence-based roadmap for future research and treatment protocols

2025 – 2026
PTSD Evaluation from Physiological Features and Biomarkers
Mentoring graduate students to design deep learning models to classify PTSD likelihood after battlefield deployment, providing a more objective evaluation

2024 – 2025
Roadmap for the Next Generation of Bioelectronic Medicine
Co-proposed technical framework for next-generation bioelectronic medicine, establishing non-invasive closed-loop neuromodulation approaches for mental health and inflammation diagnostics and precision treatment via autonomic nervous system monitoring

2024 – 2025
Cardiac Disease Detection using AI Models
Mentored graduate students to design deep learning models to classify cardiovascular disease from >800,000 ECG recording, reaching 97% accuracy

2022 – 2024
Qualcomm Institute Artificial Intelligence Program Instructor
Instructed biannual AI Development Project for 100+ undergraduates from 9 top universities in South Korean on machine learning algorithms, big data analysis, and applied AI through supervised team projects

2022 – 2023
Magnetoencephalography (MEG) Based Brain-Computer Interface (BCI)
Developed MEG-RPSnet deep learning model achieving 86% accuracy in decoding hand gestures from noninvasive brain imaging data, matching invasive electrocorticography (ECoG) performance

2023
A Bedside Vital Sign Remote Monitoring Device
Built a bedside vital sign monitoring device that can monitor live heart rate, ANG, and beat-to-beat heart rate variability (HRV) remotely

2017-2019
Spasticity Assessment Though Engineering Technology
Developed an instrumented glove for objective spasticity assessment—a project that fundamentally shaped my understanding of how engineering can directly translate into improved patient outcomes

2014-2016
One-Person Food Service
Solo-operated lunch service handling ingredient sourcing, cooking, delivery, and accounting end-to-end, all while managing academic commitments

2015-2016
Local Food Delivery Business and LAX Shuttle Service
Co-founded Feidish Inc, one of the earlist food delivery service (similar to doordash) in the region; run LAX shuttle service during breaks

2013
Coming-of-Age Challenge: Biking 650 miles in 5 Days at 18
Rode 650 miles solo over five days including moutain terrian, using only a compass and a map for navigation
Publications
A Review of Vagus Nerve Stimulation For Disease: Comprehensive Theory And Evidence For Mechanisms of Action (Accepted)
Yifeng Bu, Alex Liang, Benjamin U. Hoffman, Dawn Schiehser, Oliver Case, Alan Simmons, Ruth Klaming, Andres Gottfried-Blackmore, Ravinder K. Mittal, Christopher Puleo, Hubert Lim, Imanuel Lerman
Next generation bioelectronic medicine: making the case for non-invasive closed-loop autonomic neuromodulation
Imanuel Lerman, Yifeng Bu, Rahul Singh, Harold A Silverman, Anuj Bhardwaj, Alex J Mann, Alik Widge, Joseph Palin, Christopher Puleo, Hubert Lim
Non-invasive ventral cervical magnetoneurography as a proxy of in vivo lipopolysaccharide-induced inflammation
Yifeng Bu, Jamison Burks, Kun Yang, Jacob Prince, Amir Borna, Christopher L Coe, Alan Simmons, Xin M Tu, Dewleen Baker, Donald Kimball, Ramesh Rao, Vishal Shah, Mingxiong Huang, Peter Schwindt, Todd P Coleman, Imanuel Lerman
Magnetoencephalogram-based brain–computer interface for hand-gesture decoding using deep learning
Yifeng Bu, Deborah L Harrington, Roland R Lee, Qian Shen, Annemarie Angeles-Quinto, Zhengwei Ji, Hayden Hansen, Jaqueline Hernandez-Lucas, Jared Baumgartner, Tao Song, Sharon Nichols, Dewleen Baker, Ramesh Rao, Imanuel Lerman, Tuo Lin, Xin Ming Tu, Mingxiong Huang
Effects of High Frequency Spinal Cord Stimulation as Measured by Autonomic Tone and fMRI
Yifeng Bu, Taylor McClure, Rosalynn Conic, Sopyda Yin, Jamison Burks, Imanuel Lerman, Alan Simmons
Leveraging Machine Learning for Early Septicemia Detection From Noninvasive Analysis of the Autonomic Nervous System
Yifeng Bu, Abdullah Albattal, Jamison Burks, Truong Nguyen, Imanuel Lerman
Noninvasive Human Immunotyping Through Machine Learning Using the Autonomic Nervous System
Jamison Burks, Yifeng Bu, Abdullah Albattal, Truong Nguyen, Imanuel Lerman
A flexible adhesive surface electrode array capable of cervical electroneurography during a sequential autonomic stress challenge
Yifeng Bu, Jonas F Kurniawan, Jacob Prince, Andrew KL Nguyen, Brandon Ho, Nathan LJ Sit, Timothy Pham, Vincent M Wu, Boris Tjhia, Andrew J Shin, Tsung-Chin Wu, Xin M Tu, Ramesh Rao, Todd P Coleman, Imanuel Lerman
Peripheral nerve magnetoneurography with optically pumped magnetometers
Yifeng Bu, Jacob Prince, Hamed Mojtahed, Donald Kimball, Vishal Shah, Todd Coleman, Mahasweta Sarkar, Ramesh Rao, Mingxiong Huang, Peter Schwindt, Amir Borna, Imanuel Lerman
Non-invasive Targeted Gastric Vagal Complex Stimulation: Preliminary in Human Cutaneous Measures of Gastric Slow Wave Function
Imanuel Lerman, Yifeng Bu, Mingxiong Huang, Vicent Wu, Todd Coleman
Artifacts mitigation in sensors for spasticity assessment
Çağrı Yalçın, Mathew Sam, Yifeng Bu, Moran Amit, Andrew J Skalsky, Michael Yip, Tse Nga Ng, Harinath Garudadri
A CNN segmentation-based approach to object detection and tracking in ultrasound scans with application to the vagus nerve detection
Abdullah F Al-Battal, Yan Gong, Lu Xu, Timothy Morton, Chen Du, Yifeng Bu, Imanuel R Lerman, Radhika Madhavan, Truong Q Nguyen
Patents
Neural signal detection of immune responses
Imanuel Lerman, Ramesh Rao, Ming-Xiong Huang, Todd P Coleman, Yifeng Bu
US 18/292,659